Amino Acids Powder CAS 312-84-5 D-Serine
DSerine, synthesized in the brain by serine racemase from Lserine (its enantiomer), serves as both a neurotransmitter and a
gliotransmitter by activating NMDA receptors, making them able to open if they then also bind glutamate.
Dserine is a potent agonist at the glycine site of the NMDAtype glutamate receptor. For the receptor to open, glutamate and either glycine or Dserine must bind to it. In fact, Dserine is a more potent agonist at the glycine site on the NMDAR than glycine itself. Dserine was only thought to exist in bacteria until relatively recently; it was the second D amino acid discovered to naturally exist in humans, present as a signalling molecule in the brain, soon after the discovery of Daspartate..
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