|Description||S100A6 rabbit polyclonal|
|Protein full name||Protein S100-A6|
|Synonyms||5B10, Calcyclin, Prolactin receptor-associated protein, S100 calcium-binding protein A6, S100a6, Cacy|
|Immunogen||KLH conjugated Synthetic peptide corresponding to Mouse S100A6|
|Subcellular location||Cell membrane, Cytoplasm, Nucleus|
|Uniprot ID||P14069, P05964|
|Species||Human, Mouse, Rat||Human, Mouse, Rat|
|Dilution||1: 1000-1: 2000||1: 1000-1: 2000|
|Positive tissue||colon, testis, skin||colon cancer, small intestine, lung, testis, skin|
Calcyclin, also known as Protein S100-A6, growth factor-inducible protein 2A9, S-100 calcium-binding protein A6 (S-100A6) or MLN 4, is a homodimeric member of the S-100 calcium-binding protein family whose expression is upregulated in proliferating and differentiating cells. It may function as calcium sensor and modulator, contributing to cellular calcium signaling.Calcyclin is inducible by growth factors and overexpressed in acute myeloid leukemias. It is expressed in a cell-specific manner in subpopulations of neurons and astrocytes and in epithelial cells and fibroblasts. Calcyclin is a specific target of S-100B protein in vivo. The binding of Calcyclin to S-100B is stabilized by S-100B-bound calcium and zinc. Calcyclin associates with both Annexin XI and CacyBP (calcyclin-binding protein). It functions to activate several processes along the calcium signal transduction pathway including the regulation of cell growth, proliferation, secretion and exocytosis.
|Immunohistochemistry analysis of paraffin-embedded human colon using S100A6 (GB111078) at dilution of 1: 1000|
|Immunohistochemistry analysis of paraffin-embedded mouse testis using S100A6 (GB111078) at dilution of 1: 1000|
|Immunohistochemistry analysis of paraffin-embedded rat testis using S100A6 (GB111078) at dilution of 1: 1000|
|Immunohistochemistry analysis of paraffin-embedded mouse skin using S100A6 (GB111078) at dilution of 1: 1000|
|Immunohistochemistry analysis of paraffin-embedded rat skin using S100A6 (GB111078) at dilution of 1: 1000|
|Store at -20 ºC for one year. Avoid repeated freeze/ thaw cycles.|
|PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.|
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Wuhan Servicebio Technology Co., Ltd. was founded in 2007, headquartered in Wuhan Optical Valley Biological City, is a high-tech enterprise specializing in providing technical services and scientific research products for life and health science research. With more than 1000 employees and more than 40 service centers in large and medium-sized cities across the country, it can provide support and service to scientists who explore the mysteries of life in an all-round way.
The company has strong scientific research and service strength, has antibody research and development and production center, ultra-micro pathology center, pathological detection center, SPF experimental animal center and other technical platforms, (the company also) has a complete set of experimental platforms, instruments and equipment for pathological immune detection and analysis, and mastered the technical core and patented technology, and independently developed and optimized a variety of experimental methods and processes, and developed a number of matching reagents and consumables. The company has a special R & D team to produce and verify antibodies. Laboratory consumables centrifugal tubes and suckers have formed large-scale production and can be automated packaged. We can provide experimental design, method optimization, Experimental operation, analysis and testing, reagent consumables and other omni-directional integrated scientific research and technical services for customers.
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