Custom peptide synthesis 98% pure riptorelina/triptoreline/Triptorelin
Acetate peptides CAS 57773-63-4
What is Triptorelin?
Product Name | Triptorelin Acetate |
Sequence | Glp-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 |
Cas No. | 57773-63-4 |
Molecular Formula | C64H82N18O13 |
Molecular Weight | 1311.46 |
Purity (HPLC) | 98.0% min. |
Appearance | White powder |
Single Impurity (HPLC) | 1.0%max |
Amino Acid Composition | ±10% of theoretical |
Peptide Content (N%) | ≥80.0% |
Water Content(Karl Fischer) | ≤6.0% |
Acetate Content (HPIC) | ≤15.0% |
MS(ESI) | Consistent |
Mass Balance | 95.0~105.0% |
Specific Rotation (20/D) | -65.0~-75.0°(c=0.5 1%HAc) |
Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction. Triptorelin is marketed under the brand names Decapeptyl (Ipsen) and Diphereline and Gonapeptyl (Ferring Pharmaceuticals). In the United States, it is sold by Watson as Trelstar.In Iran Triptorelin is marketed under the brand name Variopeptyl.