Pharmaceutical Raw Material Piperonyl butoxide CAS: 51-03-6 Light Yellow Liquild
Description:
Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is a waxy white solid. It is a synergist. That is, despite having no pesticidal activity of its own, it enhances the potency of certain pesticides such as carbamates, pyrethrins, pyrethroids, and rotenone.It is a semisynthetic derivative of safrole.
Basic Information:
Chemical name: Piperonyl butoxide
MF: C19H30O5
MW: 338.44
CAS: 51-03-6
Appearance: light yellow liquild
Package: 200kg/metal bucket
COA:
| Product name | piperonyl butoxide | ||
| CAS No. | 51-03-6 | Outer Packing | 200kg |
| Production date | 2017.10.15 | Shelf life | 2 years |
| Standard adopted | Enterprise Standard | ||
| Items of analysis | Specification | Results | |
| Appearance Density | Light yellow liquild 1.0400~1.0700 | Light yellow liquild 1.0640 | |
| refractive index Water | 1.4850~1.5100 ≤0.2% | 1.5067 0.02% | |
| acid assay | ≤0.15% ≥95% | 0.03% 95.10 % | |
| Conclusion | Qualified | ||
Mechanism of action:
PBO acts as an insecticide synergist by inhibiting the natural defense mechanisms of the insect, the most important of which is the mixed-function oxidase system, (MFOs) also known as the cytochrome P-450 system. The MFO system is the primary route of detoxification in insects, and causes the oxidative breakdown of insecticides such as pyrethrins and the synthetic pyrethroids - thus when PBO is added, higher insecticide levels remain in the insect to exercise their lethal effect.An important consequence of this property is that, by enhancing the activity of a given insecticide, less may be used to achieve the same result.
PBO does not appear to have a significant effect on the MFO system in humans.PBO is found to be an efficacious, low-potency, neutral antagonist of G-protein-coupled CB1 receptors.
Other synergists for pyrethroid insecticides include Sesamex and "Sulfoxide" (not to be confused with the functional group).
How should this medicine be used?
Pyrethrin and piperonyl butoxide comes as a shampoo to apply to the skin and hair. It is usually applied to the skin and hair in two or three treatments. The second treatment must be applied 7-10 days after the first one. Sometimes a third treatment may be necessary, as recommended by your doctor. Follow the directions on your prescription label or the package label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use pyrethrin and piperonyl butoxide shampoo exactly as directed. Do not use more or less of it or use it more often than directed on the package label or prescribed by your doctor.
The package label gives you an estimate of how much shampoo you will need based on your hair length. Be sure to use enough shampoo to cover all of your scalp area and hair.
Pyrethrin and piperonyl butoxide shampoo should only be used on the skin or hair and scalp. Avoid getting pyrethrin and piperonyl butoxide shampoo in your eyes, nose, mouth, or vagina. Do not use it on your eyebrows or eyelashes.
If pyrethrin and piperonyl butoxide shampoo gets in your eyes, flush them with water right away. If your eyes are still irritated after flushing with water, call your doctor or get medical help right away.
Packing:
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Pharmaceutical Raw Material Piperonyl butoxide CAS: 51-03-6 Light Yellow Liquild