Argireline: Dermatologist weighs anti-aging ingredients

2021-11-22 11:59:25 By : Harley Jiang

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Even if you have a dedicated anti-aging program, you may still notice fine lines and wrinkles around your eyes or on your forehead. This is the natural part of aging, and there is nothing to be ashamed of, but when they start to appear, some of us might look for serums and moisturizers that promise to "smooth" or "reverse". They may even make some people consider more invasive procedures such as fillers or Botox.

But before you take this step, there is a product that is popular on TikTok, and people say that it can be a needle-free and painless way to prevent wrinkles. The Ordinary's Argireline solution is called "Bottled Botox" by some users on the app and is very popular. The #botoxinabottle tag has been viewed more than 12 million times, and the #argireline tag has been viewed more than 3 million times. Both are full of videos of people testing solutions, some say that the product helps improve the appearance of fine lines and wrinkles.

This sounds too good to be true, right? This is why we asked two top dermatologists whether this anti-aging ingredient meets the requirements of the promotion.

Argireline is the brand name for the peptide Acetyl Hexapeptide-3 or Acetyl Hexapeptide-8. Peptides are amino acids that help you make proteins (such as collagen and elastin), so they are common ingredients in beauty products, said Dr. Dendy Engelman, a board-certified dermatologist in New York City.

Dr. Joshua Zeichner, director of cosmetic and clinical research at the Department of Dermatology at Mount Sinai Hospital in New York, said that similar to Botox, Argireline's role is to inhibit the ability of nerves to release signals to muscles, thereby limiting sports cities that cause wrinkles.

Engelman added that it was one of the first external ingredients to be shown to have a certain effect on muscle contraction.

"Argireline is the closest we have to botulinum toxin in the cream," Zeichner said. "That said, creams containing Argireline are not close to the effects provided by botulinum toxin itself."

He said that wrinkles, such as the crow's feet around the eyes or the vertical "11" line on the forehead, are caused by the contraction of the deep muscles of the skin. The injection treatment you receive in the dermatologist’s office can be specifically targeted at the position and depth required to limit these contractions. When applying the Argireline solution to the skin, Zeichner said that it is questionable how deep the cream penetrates, and the effect varies from person to person.

Having said that, based on anecdotes and specific studies, there is some evidence that it may help improve the appearance of wrinkles.

Engelman said: "The way I get along with the patients I talk about is that it is certainly worth a try, especially if it is The Ordinary's $7 serum." "It really has almost no side effects, if any, And there are some results, people say it can reduce wrinkles by 10% to 30%, depending on the research you read."

For those who are afraid of needles or know that they will never go the Botox route, this may be worth a try, especially considering that some options cost less than your takeaway order.

"Is this the holy grail of anti-aging? No," Engelman said. "But if you have this in your budget and you are curious, is it worth a try... Anyway, I think it is certainly feasible, and if they are my patients, I would not object to it. But I do Want to lower their expectations of looking 20 years younger."

If you want to try it, there are many formulas on the market that contain Argireline, Engelman said, many of which also contain other beneficial additives such as other peptides and moisturizing ingredients. Here are four options to consider.

The Ordinary's Argireline solution is the most popular (and most affordable) way to incorporate this ingredient into your daily work. According to the brand, a formula with a higher water content may increase the effectiveness of Argireline, which is why the formula is water-based. The Ordinary recommends applying a few drops to the forehead and around the eyes twice a day.

Engelman said that if you want to see benefits from this ingredient, it may appear on the superficial wrinkles around your eyes. This is why an eye cream like this is a good choice. It contains a concentrated mixture of peptides, including Argireline, which the brand claims helps reduce the appearance of deep and fine eye wrinkles.

Another option from Engelman, this treatment with Argireline is applied directly to the problem area. It has advanced filling balls, a concentrated terpolymer mixture, and sodium hyaluronate for plumping the skin, which together create a smoother base for your makeup or fresh makeup.

This formula of The Ordinary also contains this ingredient. Although it is more expensive than other Argireline solutions, it is still in the affordable range and includes other effective peptides and moisturizing hyaluronic acid.

This top pick has an average rating of 4.4 stars and comes from more than 2,000 reviews. It contains Argireline, Vitamin C and Matrixyl 3000, which is another peptide that, according to the brand, can help stimulate collagen production. We haven't tried it ourselves, but verified reviewers say it helps reduce the appearance of fine lines and sunspots-some people even call it the "Fountain of Youth".

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Emma Stessman is the editorial assistant of Shop TODAY.