Be cautious with this combination

L-arginine may lower blood pressure. Taking L-arginine and drugs that lower blood pressure may cause blood pressure to be too low. Monitor your blood pressure closely.

Sildenafil can lower blood pressure. L-arginine can also lower blood pressure. Taking sildenafil with L-arginine may cause hypotension. But most people seem to be doing well when taking these products.

L-arginine may lower blood pressure. Taking L-arginine and drugs that lower blood pressure may cause blood pressure to be too low. Monitor your blood pressure closely.

L-arginine may lower blood pressure. Taking L-arginine and drugs that lower blood pressure may cause blood pressure to be too low. Monitor your blood pressure closely.

L-arginine may slow blood clotting. Taking L-arginine and drugs that slow blood clotting may increase the risk of bruising and bleeding.

L-arginine may lower blood sugar levels. Taking L-arginine and diabetes medications may cause blood sugar to drop too low. Monitor your blood sugar closely.

L-arginine seems to lower blood pressure. Isoproterenol is a medicine used to lower blood pressure. Taking L-arginine and isoproterenol may cause your blood pressure to go too low.

L-arginine may increase the amount of potassium in the body. Some "water pills" may also increase potassium in the body. Taking L-arginine and some "water pills" may cause too much potassium in the body.

Be careful with this combination

L-arginine may increase testosterone levels. But it is not clear whether this is a big problem. People taking testosterone should be cautious until they learn more about this potential interaction.

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Giger, U., Buchler, M., Farhadi, J., Berger, D., Husler, J., Schneider, H., Krahenbuhl, S., and Krahenbuhl, L. Abdominal surgery-a randomized controlled trial study. Ann.Surg.Oncol. 2007;14(10):2798-2806. View the summary.

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Gryglewski, RJ, Grodzinska, L., Kostka-Trabka, E., Korbut, R., Bieroon, K., Goszcz, A. and Slawainski, M. Treatment with L-arginine may stimulate the production of nitric oxide Patients with peripheral arterial obstructive disease. Vienna. Klin. Wochenschr. 1996;108(4):111-116. View the summary.

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Higashi, Y., Oshima, T., Ono, N., Hiraga, H., Yoshimura, M., Watanabe, M., Matsuura, H., Kambe, M. and Kajiyama, G. Intravenous administration of L- Arginine inhibits angiotensin-converting enzyme in the human body. J Clin. Endocrinol. Metab 1995;80(7):2198-2202. View the summary.

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Houwing, RH, Rozendaal, M., Wouters-Wesseling, W., Beulens, JW, Buskens, E. and Haalboom, JR A randomized double-blind evaluation of the effect of nutritional supplementation on the prevention of hip pressure ulcers-fracture patients. Clinical nutrition. 2003;22(4):401-405. View the summary.

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Huang, CC, Lin, TJ, Lu, YF, Chen, CC, Huang, CY and Lin, WT L-arginine supplements protect against oxidative stress induced by exhaustive exercise in young rat tissues. Chinese Journal of Physiology 10-31-2009;52(5):306-315. View the summary.

Huang, CC, Tsai, SC and Lin, WT L-arginine have a potential synergistic effect on the oxidative and inflammatory stress induced by acute exercise in aging rats. Exp. Gerontol. 2008;43(6):571-577. View the summary.

Hughes, N., Mason, S., Jeffery, P., Welton, H., Tobin, M., O'Shea, C. and Browne, M. A comparative clinical study investigated the content of 8% strontium acetate and Comparison of 1040 ppm sodium fluoride and a commercially available control dentifrice containing 8% arginine, calcium carbonate and 1450 ppm sodium monofluorophosphate in reducing dentin hypersensitivity. J Clin. Dent. 2010;21(2):49-55. View the summary.

Jahangir, E., Vita, JA, Handy, D., Holbrook, M., Palmisano, J., Beal, R., Loscalzo, J., and Eberhardt, RT Effect of L-arginine and creatine on vascular function Affects and homocysteine ​​metabolism. Vascular medicine. 2009;14(3):239-248. View the summary.

Jezova, D., Makatsori, A., Smriga, M., Morinaga, Y., and Duncko, R. Subchronic treatment with an amino acid mixture of L-lysine and L-arginine can change high-quality The subject's neuroendocrine activation anxiety during psychosocial stress. Nutritional neuroscience. 2005;8(3):155-160. View the summary.

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Jiang, ZM, Gu, ZY, Chen, FL, Wang, XR, Li, ZJ, Xu, Y., and Li, R. [The effect of immune-enhancing enteral nutrition on plasma amino acids, intestinal permeability and clinical outcome (A 120 randomized, double-blind, controlled, multi-center clinical trials)]. China First Science. Science. Learning. Yuan Xue. Bao. 2001;23(5):515-518. View the summary.

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Kato, GJ and Gladwin, MT The evolution of new small molecule therapies for sickle cell vascular disease. Journal of the American Medical Association 12-10-2008;300(22):2638-2646. View the summary.

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Kawano, H., Motoyama, T., Hirai, N., Kugiyama, K., Yasue, H. and Ogawa, H. Administration of L-arginine ameliorated endothelial dysfunction in hypercholesterolemia: oxidative response The possible role of excitement. Atherosclerosis 2002;161(2):375-380. View the summary.

Kernohan, AF, McIntyre, M., Hughes, DM, Tam, SW, Worcel, M. and Reid, JL Oral yohimbine/L-arginine combination (NMI 861) for the treatment of male erectile dysfunction: medicine Study on the interaction of kinetics and pharmacodynamics with intravenous nitroglycerin in healthy male subjects. Br J Clin. Pharmacol. 2005;59(1):85-93. View the summary.

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Lekakis, JP, Papathanassiou, S., Papaioannou, TG, Papamichael, CM, Zakopoulos, N., Kotsis, V., Dagre, AG, Stamatelopoulos, K., Protogerou, A. and Stamatelopoulos, SF Oral L-arginine Improve endothelial dysfunction in patients with essential hypertension. International Heart Journal 2002;86(2-3):317-323. View the summary.

Little, JA, Hauser, KP, Martyr, SE, Harris, A., Maric, I., Morris, CR, Suh, JH, Taylor, J., Castro, O., Machado, R., Kato, G., And Gladwin, MT supplemented with L-arginine or inhibited phosphodiesterase 5 on the hematology, biochemistry, and cardiopulmonary effects of patients with sickle cell disease treated with hydroxyurea. Eur.J Haematol. 2009;82(4):315-321. View the summary.

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Martina, V., Masha, A., Gigliardi, VR, Brocato, L., Manzato, E., Berchio, A., Massarenti, P., Settanni, F., Della, Casa L., Bergamini, S., And Iannone, A. Long-term use of N-acetylcysteine ​​and L-arginine can reduce endothelial activation and systolic blood pressure in patients with type 2 diabetes and hypertension. Diabetes Care 2008;31(5):940-944. View the summary.

Masha, A., Manieri, C., Dinatale, S., Bruno, GA, Ghigo, E. and Martina, V. Long-term use of N-acetylcysteine ​​and L-arginine can restore polycystic ovarian synthesis Sign the patient’s gonadal function. J Endocrinol. Invest 2009;32(11):870-872. View the summary.

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Nitenberg, A., Ledoux, S., Attali, JR, and Valensi, P. [Deferoxamine in diabetic patients improved the coronary response to cold tests and increased flow rate, but L-arginine did not improve]. Arch. Mal Coeur Vaiss. 1997;90(8):1037-1041. View the summary.

O'Rourke, DJ, Ryan, S., Salomons, G., Jakobs, C., Monavari, A. and King, MD Guanidinoacetate methyltransferase (GAMT) deficiency: dyskinesia delayed and expressive Language reservation. Dev.Med.Child Neurol. 2009;51(5):404-407. View the summary.

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Okamoto, Y., Okano, K., Izuishi, K., Usuki, H., Wakabayashi, H. and Suzuki, Y. Preoperative oral arginine and omega-3 systemic inflammation and infection after lipogastrectomy The weakened acid of the disease supplements immune nutrition. World J Surgery. 2009;33(9):1815-1821. View the summary.

Olek, RA, Ziemann, E., Grzywacz, T., Kujach, S., Luszczyk, M., Antosiewicz, J. and Laskowski, R. During the repeated Wingate anaerobic test, a single oral dose of arginine would not Affect performance. J Sports Med.Phys.Fitness 2010;50(1):52-56. View the summary.

Ozbek, M., Erdogan, M., Karadeniz, M., Cetinkalp, S., Ozgen, AG, Saygili, F., Yilmaz, C. and Tuzun, M. Evaluation of β-cell dysfunction and the use of mixed diet tolerance tests Newly diagnosed type 2 diabetes patients take L-arginine orally. Exp.Clin.Endocrinol.Diabetes 2009;117(10):573-576. View the summary.

Palloshi, A., Fragasso, G., Piatti, P., Monti, LD, Setola, E., Valsecchi, G., Galluccio, E., Chierchia, SL and Margonato, A. Oral L-arginine system Blood pressure, symptoms, and endothelial function in patients with hypertension, positive exercise tests, and normal coronary arteries. Am J Cardiol 4-1-2004;93(7):933-935. View the summary.

Park, KG, Heys, SD, Blessing, K., Kelly, P., McNurlan, MA, Eremin, O. and Garlick, PJ The stimulation of dietary L-arginine on human breast cancer. Clinical Science (London) 1992;82(4):413-417. View the summary.

The enhancement of endothelial function after exercise training in Parnell, MM, Holst, DP and Kaye, DM is related to the increase of L-arginine transport in human heart failure. Clinical Science (London) 2005;109(6):523-530. View the summary.

Pedrinelli, R., Ebel, M., Catapano, G., Dell'Omo, G., Ducci, M., Del, Chicca M., and Clerico, A. Pressor, L-arginine for kidney and endocrine Affect essential hypertension patients. Eur.J Clin.Pharmacol. 1995;48(3-4):195-201. View the summary.

Petrou, I., Heu, R., Stranick, M., Lavender, S., Zaidel, L., Cummins, D., Sullivan, RJ, Hsueh, C. and Gimzewski, JK Breakthrough treatments for dentin hypersensitivity: How can dental products containing 8% arginine and calcium carbonate effectively alleviate tooth sensitivity? J Clin. Dent. 2009;20(1):23-31. View the summary.

Pezza, V., Bernardini, F., Pezza, E., Pezza, B. and Curion, M. Study on supplementation of oral l-arginine in hypertensive patients treated with enalapril and hydrochlorothiazide. Am.J hypertension. 1998;11(10):1267-1270. View the summary.

Piatti, PM, Monti, LD, Valsecchi, G., Magni, F., Setola, E., Marchesi, F., Galli-Kienle, M., Pozza, G., and Alberti, KG long-term oral L-arginine Acid administration can improve peripheral and liver insulin sensitivity in patients with type 2 diabetes. Diabetes Care 2001;24(5):875-880. View the summary.

Pryor, JP, Blandy, JP, Evans, P., Chaput De Saintonge, DM and Usherwood, M. A controlled clinical trial of arginine in oligospermia infertile men. Br J Urol. 1978;50(1):47-50. View the summary.

Puiman, PJ, Stoll, B., van Goudoever, JB and Burrin, DG Intestinal arginine does not increase the blood flow of the superior mesenteric artery, but it induces mucosal growth in newborn pigs. J nutrition. 2011;141(1):63-70. View the summary.

Quyyumi, AA Does acute improvement of endothelial dysfunction in coronary artery disease improve myocardial ischemia? Double-blind comparison of parenteral D- and L-arginine. J Am Coll. Cardiol 1998; 32(4): 904-911. View the summary.

Ralph, AP, Kelly, PM and Anstey, NM L-arginine and vitamin D: new adjuvant immunotherapy for tuberculosis. Trending microorganisms. 2008;16(7):336-344. View the summary.

Riso, S., Aluffi, P., Brugnani, M., Farinetti, F., Pia, F. and D'Andrea, F. Postoperative enteral immunonutrition for patients with head and neck cancer. Clin. Nutr 2000;19(6):407-412. View the summary.

Ruel, M., Beanlands, RS, Lortie, M., Chan, V., Camack, N., deKemp, RA, Suuronen, EJ, Rubens, FD, DaSilva, JN, Sellke, FW, Stewart, DJ, and Mesana , TG oral L-arginine simultaneous treatment can improve the efficacy of surgical angiogenesis in patients with severe diffuse coronary artery disease: a randomized controlled trial of endothelial regulation in angiogenesis treatment. J Thorac. Cardiovasc. Surg. 2008;135(4):762-70, 770. View abstract.

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Rytlewski, K., Olszanecki, R., Lauterbach, R., Grzyb, A., and Basta, A. The effect of oral L-arginine on fetal status and neonatal outcomes with preeclampsia: a preliminary report. Basic clinical. Pharmacology. Toxicology. 2006;99(2):146-152. View the summary.

Sakurai, Y., Masui, T., Yoshida, I., Tonomura, S., Shoji, M., Nakamura, Y., Isogaki, J., Uyama, I., Komori, Y. and Ochiai, M. Wai Randomized clinical trial on the effect of immune-enhancing enteral formula on the metabolic and immune status of patients undergoing esophagectomy during surgery. World J Surgery. 2007;31(11):2150-2157. View the summary.

Schaefer, A., Piquard, F., Geny, B., Doutreleau, S., Lampert, E., Mettauer, B. and Lonsdorfer, J. L-arginine reduces the increase in plasma lactic acid and ammonia caused by exercise. Int.J Sports Med. 2002;23(6):403-407. View the summary.

Schellong, SM, Boger, RH, Burchert, W., Bode-Boger, SM, Galland, A., Frolich, JC, Hundeshagen, H. and Alexander, K. The dose of intravenous L-arginine on muscle blood is related Affecting blood flow in the calf of patients with peripheral vascular disease: H215O positron emission tomography study. Clinical Science (London) 1997;93(2):159-165. View the summary.

Schilling, J., Vranjes, N., Fierz, W., Joller, H., Gyurech, D., Ludwig, E., Marathias, K. and Geroulanos, S. Clinical outcome and immunology of postoperative arginine , Omega-3 fatty acids and nucleotide-rich enteral nutrition: a randomized prospective comparison with standard enteral and low-calorie/low-fat IV solutions. Nutrition 1996;12(6):423-429. View the summary.

Schlaich, MP, Ahlers, BA, Parnell, MM and Kaye, DM β-adrenergic receptor-mediated nitric oxide-dependent vasodilation is abnormal in early hypertension: recovery by L-arginine. J Hypertension. 2004;22(10):1917-1925. View the summary.

Schlaich, MP, Jacobi, J., John, S., Delles, C., Fleischmann, I., and Schmieder, RE L-arginine infusion is an appropriate tool to assess endothelium-dependent vasodilation of the human renal vascular system ? Clinical Science (London) 2000;99(4):293-302. View the summary.

Schlaich, MP, Oehmer, S., Schneider, MP, Delles, C., Schmidt, BM and Schmieder, RE nitric oxide synthase inhibition and L-arginine on renal hemodynamics in young patients with high cardiovascular risk Influence. Atherosclerosis 2007;192(1):155-160. View the summary.

Schon, T., Elias, D., Moges, F., Melese, E., Tessema, T., Stendahl, O., Britton, S., and Sundqvist, T. Arginine as a adjuvant to Chemistry Tuberculosis. Eur. Respir. J 2003;21(3):483-488. View the summary.

Schramm, L., La, M., Heidbreder, E., Hecker, M., Beckman, JS, Lopau, K., Zimmermann, J., Rendl, J., Reiners, C., Winderl, S., Wanner , C., and Schmidt, HH L-arginine deficiency and supplementation in experimental acute renal failure and human kidney transplantation. Kidney International 2002;61(4):1423-1432. View the summary.

Schulze, F., Glos, S., Petruschka, D., Altenburg, C., Maas, R., Benndorf, R., Schwedhelm, E., Beil, U., and Boger, RH L-arginine increase Triglycerides-Simvastatin's lowering effect on patients with elevated plasma triglycerides. Nutr. Res 2009;29(5):291-297. View the summary.

Scibona, M., Meschini, P., Capparelli, S., Pecori, C., Rossi, P. and Menchini Fabris, GF [L-arginine and male infertility]. Minerva Urol.Nefrol. 1994;46(4):251-253. View the summary.

Senkal, M., Mumme, A., Eickhoff, U., Geier, B., Spath, G., Wulfert, D., Joosten, U., Frei, A. and Kemen, M. Early postoperative enteral immunization Nutrition: Comparative analysis of clinical outcomes and costs of surgical patients. Critical Nursing Medicine. 1997; 25(9): 1489-1496. View the summary.

Senkal, M., Zumtobel, V., Bauer, KH, Marpe, B., Wolfram, G., Frei, A., Eickhoff, U. and Kemen, M. Outcome and cost of enteral immunonutrition during the perioperative period Benefits of receiving elective upper gastrointestinal surgery: a prospective randomized study. Arch.Surg. 1999;134(12):1309-1316. View the summary.

Settergren, M., Bohm, F., Malmstrom, RE, Channon, KM and Pernow, J. L-arginine and tetrahydrobiopterin can prevent ischemia/reperfusion in patients with type 2 diabetes and coronary artery disease Endothelial dysfunction. Atherosclerosis 2009;204(1):73-78. View the summary.

Shao, A. and Hathcock, JN Risk assessment of amino acids taurine, L-glutamine and L-arginine. Regul. Toxicol. Pharmacol 2008;50(3):376-399. View the summary.

Shigemi, R., Fukuda, M., Suzuki, Y., Morimoto, T., and Ishii, E. L-arginine is effective against MELAS stroke-like episodes associated with the G13513A mutation. Brain Development 2011;33(6):518-520. View the summary.

Siasos, G., Tousoulis, D., Vlachopoulos, C., Antoniades, C., Stefanadi, E., Ioakeimidis, N., Andreou, I., Zisimos, K., Papavassiliou, AG, and Stefanadis, C. Short Long-term treatment with L-arginine can prevent the damage of endothelial function and blood vessel elasticity in young people caused by smoking. International Heart Journal 6-6-2008;126(3):394-399. View the summary.

Sieroszewski, P., Suzin, J., and Karowicz-Bilinska, A. Ultrasound evaluation of the treatment of intrauterine growth restriction with a nitric oxide donor (L-arginine). J Matern. Fetal Neonatal Medicine. 2004;15(6):363-366. View the summary.

Slawinski, M., Grodzinska, L., Kostka-Trabka, E., Bieron, K., Goszcz, A., and Gryglewski, RJ L-arginine-a non-synthetic substrate-it is in the treatment of Peripheral artery disease: comparison with initial results of placebo. Acta Physiology. 1996;84(4):457-458. View the summary.

Smith, SD, Wheeler, MA, Foster, HE, Jr. and Weiss, RM improved the symptom score of interstitial cystitis during oral L-arginine treatment. J Urol. 1997;158(3 Pt 1):703-708. View the summary.

Smriga, M., Ando, ​​T., Akutsu, M., Furukawa, Y., Miwa, K. and Morinaga, Y. Oral treatment with L-lysine and L-arginine can reduce anxiety and anxiety in healthy people. Basal cortisol level. Biomed. Res 2007;28(2):85-90. View the summary.

Smulders, RA, Aarsen, M., Teerlink, T., De Vries, PM, Van Kamp, GJ, Donker, AJ and Stehouwer, CD Normal subjects with L-arginine and L-lysine infusion Hemodynamic and biochemical reactions: L-arginine-induced vasodilation cannot be explained by the non-specific effects of cationic amino acids. Clinical Science (London) 1997; 92(4): 367-374. View the summary.

Smulders, RA, Stehouwer, CD, Olthof, CG, Van Kamp, GJ, Teerlink, T., De Vries, PM and Donker, AJ plasma endothelin levels and intravenous L-arginine infusion versus uncomplicated insulin Relying on the patient's blood vessels affects diabetes. Clin. Sci (London) 1994; 87(1): 37-43. View the summary.

Snyderman, CH, Kachman, K., Molseed, L., Wagner, R., D'Amico, F., Bumpous, J. and Rueger, R. Reduce postoperative infections through immune-enhancing nutritional supplements. Laryngoscope 1999;109(6):915-921. View the summary.

Song, JX, Qing, SH, Huang, XC and Qi, DL The effect of parenteral nutrition supplementation with L-arginine on postoperative immune function in patients with colorectal cancer. Di Yi, Jun, Yi, Da, Xue, Xue, Bao. 2002;22(6):545-547. View the summary.

Sozykin, AV, Noeva, EA, Balakhonova, TV, Pogorelova, OA and Men'shikov, MI [Effect of L-arginine on platelet aggregation, endothelial function and exercise tolerance in patients with stable angina]. Te Ake. 2000;72(8):24-27. View the summary.

Srivastava, S. and Agarwal, A. The effect of anion channel blockers on the effect of L-arginine in the sperm of asthenospermia men. Andrology 2010;42(2):76-82. View the summary.

Stanislavov, R., Nikolova, V. and Rohdewald, P. Using Prelox to improve semen parameters: a randomized, double-blind, placebo-controlled, crossover trial. Phytother. Res 2009;23(3):297-302. View the summary.

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Stechmiller, JK, Langkamp-Henken, B., Childress, B., Herrlinger-Garcia, KA, Hudgens, J., Tian, ​​L., Percival, SS, and Steele, R. Supplementation of arginine does not increase serum level. Nitric oxide levels are among elderly nursing home residents with pressure ulcers. Biol.Res nurse. 2005;6(4):289-299. View the summary.

Stokes, GS, Barin, ES, Gilfillan, KL and Kaesemeyer, WH Interaction of L-arginine, isosorbide mononitrate and angiotensin II inhibitors on arterial pulse waves. I am J with high blood pressure. 2003;16(9 Pt 1):719-724. View the summary.

Sullivan, KJ, Kissoon, N., Sandler, E., Gauger, C., Froyen, M., Duckworth, L., Brown, M., and Murphy, S. Oral arginine supplements on exhaled breath monoxide oxidation Nitrogen concentration affects sickle cell anemia and acute chest syndrome. J Pediatr Hematol.Oncol. 2010;32(7):e249-e258. View the summary.

Sun, T., Zhou, WB, Luo, XP, Tang, YL and Shi, HM Oral L-arginine supplementation in the treatment of acute myocardial infarction: a meta-analysis of randomized controlled trials. Clin. Cardiol 2009; 32(11):649-652. View the summary.

Sunderland, KL, Greer, F. and Morales, J. The maximum oxygen uptake and ventilatory threshold of trained cyclists are not affected by 28-day L-arginine supplementation. J Strength. Cond. Res 2011;25(3):833-837. View the summary.

Suzuki, T., Hayase, M., Hibi, K., Hosokawa, H., Yokoya, K., Fitzgerald, PJ, Yock, PG, Cooke, JP, Suzuki, T., and Yeung, AC The impact of local delivery The effect of L-arginine on restenosis in human stents. Am J Cardiol 2-15-2002; 89(4):363-367. View the summary.

Sydow, K., Schwedhelm, E., Arakawa, N., Bode-Boger, SM, Tsikas, D., Hornig, B., Frolich, JC, and Boger, RH ADMA and oxidative stress are high homotypic endothelial functions The cause of the disorder (e) Anemia: the influence of L-arginine and B vitamins. Cardiovasc. Res 2003;57(1):244-252. View the summary.

Takasaki, A., Tamura, H., Miwa, I., Taketani, T., Shimamura, K., and Sugino, N. Endometrial growth and uterine blood flow: a preliminary study to improve endometrial thickness . Fertilize. 2010;93(6):1851-1858. View the summary.

Tan, B., Li, XG, Kong, X., Huang, R., Ruan, Z., Yao, K., Deng, Z., Xie, M., Shinzato, I., Yin, Y., and Wu, G. The dietary supplement L-arginine can enhance the immune status of early weaned piglets. Amino Acids 2009;37(2):323-331. View the summary.

Tan, B., Yin, Y., Liu, Z., Tang, W., Xu, H., Kong, X., Li, X., Yao, K., Gu, W., Smith, SB, and Wu, G. Dietary L-arginine supplements differentially regulate the expression of lipid metabolism genes in pig adipose tissue and skeletal muscle. J Nutr. Biochem. 2011;22(5):441-445. View the summary.

Tangphao, O., Grossmann, M., Chalon, S., Hoffman, BB, and Blaschke, TF. Pharmacokinetics of intravenous and oral L-arginine in normal volunteers. Br J Clin. Pharmacol. 1999;47(3):261-266. View the summary.

Tanimura, J. Research on arginine in human semen. I. The arginine content of normal and sterile human semen. Bull. Osaka Med. Sch 1967;13(2):76-83. View the summary.

Tanimura, J. Research on arginine in human semen. 2. The effect of L-arginine-HCL drugs on male infertility. Bull. Osaka Med. Sch 1967;13(2):84-89. View the summary.

Tarumoto, T., Imagawa, S., Kobayashi, M., Hirayama, A., Ozawa, K. and Nagasawa, T. Administration of L-arginine can reverse anemia associated with nephropathy. Int.J Hematology. 2007;86(2):126-129. View the summary.

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Theilmeier, G., Chan, JR, Zalpour, C., Anderson, B., Wang, BY, Wolf, A., Tsao, PS and Cooke, JP Adhesion of human monocytes with hypercholesterolemia through diet L -Arginine standardization. Arterioscler. Thromb. Vasc. Biol. 1997;17(12):3557-3564. View the summary.

Thorne, S., Mullen, MJ, Clarkson, P., Donald, AE and Deanfield, JE Early endothelial dysfunction in adults at risk of atherosclerosis: Different responses to L-arginine. J Am.Col.Cardiol. 1998; 32(1): 110-116. View the summary.

Tripathi, P. and Misra, MK The therapeutic effect of L-arginine on free radical scavenging system in ischemic heart disease. J Biochem.Biophys, India. 2009;46(6):498-502. View the summary.

Tripathi, P., Chandra, M. and Misra, MK Oral L-arginine in patients with angina or after myocardial infarction may be provided by increasing plasma superoxide dismutase and total thiols and lowering serum cholesterol and xanthine oxidase protect. Oxid.Med.Cell Longev. 2009;2(4):231-237. View the summary.

Intestinal arginine supplemented by Tsuei, BJ, Bernard, AC, Barksdale, AR, Rockich, AK, Meier, CF and Kearney, PA is metabolized to ornithine in injured patients. J Surg. Res 2005;123(1):17-24. View the summary.

Tuchman, M., Lee, B., Lichter-Konecki, U., Summar, ML, Yudkoff, M., Cederbaum, SD, Kerr, DS, Diaz, GA, Seashore, MR, Lee, HS, McCarter, RJ, Krischer, JP and Batshaw, ML A cross-sectional multicenter study of patients with urea cycle disorders in the United States. Mol. Genet. Metab 2008;94(4):397-402. View the summary.

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van den Meiracker, AH, van der Linde, NA, Broere, A., Derkx, FH and Boomsma, F. The effect of L-arginine and L-NAME on renal function in hypertensive and normotensive subjects. Kidney Disease 2002;91(3):444-451. View the summary.

Vigano, E., Badalamenti, S., Paone, G., Como, G., Finazzi, S., Tarantino, A., Galmarini, D., and Ponticelli, C. L-arginine infusion with cyclosporine Effects on the kidneys-transplant recipients receiving treatment. Transplantation Process 1994;26(5):2622-2623. View the summary.

Wachtler, P., Axel, Hilger R., Konig, W., Bauer, KH, Kemen, M. and Koller, M. The effect of preoperative enteral supplementation on the functional activity of peripheral white blood cells in patients with major surgery. Clin. Nutr 1995;14(5):275-282. View the summary.

Wallace, AW, Ratcliffe, MB, Galindez, D. and Kong, JS L-arginine infusion can dilate the coronary vascular system of patients undergoing coronary artery bypass surgery. Anesthesiology 1999;90(6):1577-1586. View the summary.

Wascher, TC, Graier, WF, Dittrich, P., Hussain, MA, Bahadori, B., Wallner, S. and Toplak, H. Effects of low-dose L-arginine on insulin-mediated vasodilation and insulin sensitivity Influence. Eur. J Clin. Invest 1997; 27(8): 690-695. View the summary.

Weitzel, LR, Mayles, WJ, Sandoval, PA and Wischmeyer, the effect of PE pharmaconutrients on cell dysfunction and microcirculation in critical diseases. Curr.Opin.Anaesthesiol. 2009;22(2):177-183. View the summary.

Wennmalm, A., Edlund, A., Granstrom, EF and Wiklund, O. Acute supplementation of nitric oxide precursor L-arginine does not improve cardiovascular function in patients with hypercholesterolemia. Atherosclerosis 1995;118(2):223-231. View the summary.

West, SG, Likos-Krick, A., Brown, P. and Mariotti, F. Oral L-arginine can improve the hemodynamic response to stress in men with hypercholesterolemia and reduce plasma homocysteine. J nutrition. 2005;135(2):212-217. View the summary.

Wideman, L., Weltman, JY, Patrie, JT, Bowers, CY, Shah, N., Story, S., Veldhuis, JD and Weltman, A. L-arginine and GHRP-2 stimulate the synergistic effect of growth hormone Men and women: modulate through exercise. Am J Physiol Regul. Integr. Comp Physiol 2000;279(4):R1467-R1477. View the summary.

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Winer, N., Brager, B., Azria, E., Tsatsaris, V., Philippe, HJ, Roze, JC, Descamps, P., Boog, G., Cynober, L. and Darmaun, D. L-fine Acid treatment of severe vascular fetal intrauterine growth restriction: a randomized double-combination controlled trial. Clinical nutrition. 2009;28(3):243-248. View the summary.

Wolf, A., Zalpour, C., Theilmeier, G., Wang, BY, Ma, A., Anderson, B., Tsao, PS and Cooke, JP Dietary L-arginine supplements can cause hypercholesterolemia Human platelet aggregation is normalized. J Am Coll. Cardiol 3-1-1997;29(3):479-485. View the summary.

Wolf, SC, Erley, CM, Kenner, S., Berger, ED and Risler, T. Does L-arginine change proteinuria and renal hemodynamics in patients with chronic glomerulonephritis and hypertension? Clinical nephropathy. 1995; 43 Supplement 1: S42-S46. View the summary.

Wolzt, M., Ugurluoglu, A., Schmetterer, L., Dorner, G., Zanaschka, G., Mensik, C. and Eichler, HG Exogenous L-arginine does not affect people induced by angiotensin II Renal vasoconstriction. Br J Clin. Pharmacol. 1998; 45(1): 71-75. View the summary.

Wu, G., Bazer, FW, Davis, TA, Kim, SW, Li, P., Marc, Rhoads J., Carey, Satterfield M., Smith, SB, Spencer, TE, and Yin, Y. Arginine Nutrition in metabolism and growth, health and disease. Amino Acids 2009;37(1):153-168. View the summary.

Xiao, XM and Li, LP L-arginine treat asymmetric fetal growth restriction. Int.J Gynaecol.Obstet. 2005;88(1):15-18. View the summary.

Xu, J., Zhong, Y., Jing, D. and Wu, Z. Preoperative enteral immunonutrition can improve the postoperative prognosis of patients with gastrointestinal cancer. World J Surgery. 2006;30(7):1284-1289. View the summary.

Yan, H., Peng, X., Huang, Y., Zhao, M., Li, F. and Wang, P. The effect of early enteral arginine supplementation on the resuscitation of severely burned patients. Burns 2007; 33(2): 179-184. View the summary.

Yin, WH, Chen, JW, Tsai, C., Chiang, MC, Young, MS and Lin, SJ L-arginine improves endothelial function and reduces LDL oxidation in patients with stable coronary artery disease. Clinical nutrition. 2005;24(6):988-997. View the summary.

Zamora, SA, Amin, HJ, McMillan, DD, Kubes, P., Fick, GH, Butzner, JD, Parsons, HG, and Scott, RB Plasma L-arginine in preterm infants with necrotizing enterocolitis In the concentration. J Pediatr 1997;131(2):226-232. View the summary.

Zhang, XZ, Ardissino, G., Ghio, L., Tirelli, AS, Dacco, V., Colombo, D., Pace, E., Testa, S. and Claris-Appiani, A. L-arginine supplement For young allogeneic kidney transplant recipients with chronic transplant dysfunction. Clinical nephropathy. 2001;55(6):453-459. View the summary.

Zhang, XZ, Ghio, L., Ardissino, G., Tirelli, AS, Dacco, V., Testa, S. and Claris-Appiani, A. L-arginine infusion on kidney and metabolism of kidney transplant recipients Influence. Clinical nephropathy. 1999;52(1):37-43. View the summary.

Zheng, Y., Li, F., Qi, B., Luo, B., Sun, H., Liu, S., and Wu, X. Application of perioperative immunonutrition in gastrointestinal surgery: random Controlled meta-analysis trials. Asia Pac.J Clin.Nutr. 2007;16 Supplement 1:253-257. View the summary.

Zhou, M. and Martindale, RG Arginine in an intensive care setting. J nutrition. 2007; 137 (6 Supplement 2): 1687S-1692S. View the summary.

Abu El-Hamd M, Hegazy EM. Comparison of the clinical efficacy of daily use of L-arginine, tadalafil and L-arginine combined with tadalafil in the treatment of elderly erectile dysfunction. Andrology. 2020; 52(7): e13640. View the summary.

Adams MR, McCredie R, Jessup W, etc. Oral L-arginine can improve endothelium-dependent expansion and reduce the adhesion of monocytes and endothelial cells in young men with coronary artery disease. Atherosclerosis 1997;129:261-9. View the summary.

Aguiar AF, Balvedi MC, Buzzachera CF, etc. L-arginine supplements will not enhance blood flow and muscle performance in healthy and physically active elderly women. European Journal of Nutrition. 2016;55(6):2053-62. View the summary.

Alvares TS, Conte CA, Paschoalin VM, etc. Acute l-arginine supplementation increases muscle blood volume, but does not increase strength performance. Appl Physiol Nutr Metab. 2012 February; 37(1): 115-26. View the summary.

Amin HJ, Zamora SA, McMillan DD, etc. Arginine supplementation can prevent necrotizing enterocolitis in premature infants. J Pediatr 2002;140:425-31. View the summary.

Andrade WB, Jacinto JL, da Silva DK, etc. L-arginine supplementation will not improve muscle function during the recovery period of resistance exercise. Appl Physiol Nutr Metab. 2018;43(9):928-936. View the summary.

Andres A, Morales JM, Praga M, etc. L-arginine reverses the antinatriuretic effect of cyclosporine in kidney transplant patients. Renin Dial Transplant 1997; 12:1437-40. View the summary.

anonymous. Arginine hydrochloride injection (trade name R-Gene 10). FDA Drug Safety Bulletin 2009; 2(2): 16-18. It can be obtained from the following website: www.fda.gov/Drugs/DrugSafety/DrugSafetyNewsletter/default.htm.

Arana V, Paz Y, González A, Méndez V, Méndez JD. L-arginine treats the healing of diabetic foot ulcers in patients. Biomed Pharmacother 2004;58:588-97. View the summary.

Armstrong DG, Hanft JR, Driver VR, etc. The effect of oral nutritional supplements on wound healing of diabetic foot ulcers: a prospective randomized controlled trial. Diabetes Medicine 2014; 31(9): 1069-77. View the summary.

Bauer JD, Isenring E, Waterhouse M. The effectiveness of specialized oral nutritional supplements on the prognosis of patients with chronic wounds: a pragmatic randomized study. J Hum Nutr diet. October 2013; 26(5):452-8. View the summary.

Bednarz B, Jaxa-Chamiec T, Maciejewski P, etc. The efficacy and safety of oral l-arginine in the treatment of acute myocardial infarction. Results of a multicenter, randomized, double-blind, placebo-controlled ARAMI pilot trial. Kardiol Pol 2005; 62: 421-7. View the summary.

Binet Q, Dufour I, Agneessens E, etc. The second case of young man with acute pancreatitis induced by L-arginine. Clinical J Gastroenterology. 2018;11(5):424-427. View the summary.

Blum A, Hathaway L, Mincemoyer R, etc. The effect of oral L-arginine on endothelium-dependent vasodilation and inflammation markers in healthy postmenopausal women. J Am Coll Cardiol 2000; 35: 271-6. View the summary.

Blum A, Hathaway L, Mincemoyer R, etc. Oral L-arginine is a drug treatment for patients with coronary artery disease. Circulation 2000; 101: 2160-4. View the summary.

Blum A, Porat R, Rosenschein U, etc. The clinical and inflammatory effects of dietary L-arginine on patients with refractory angina pectoris. Am J Cardiol 1999; 15:1488-90. View the summary.

Bocchi EA, Vilella de Moraes AV, Esteves-Filho A, etc. L-arginine can lower the heart rate and improve the hemodynamics of severe congestive heart failure. Clinical Cardiology 2000; 23:205-10. View the summary.

Bode-Boger SM, Boger RH, Galland A, etc. L-arginine-induced vasodilation in healthy people: pharmacokinetic-pharmacodynamic relationship. Br J Clin Pharmacol 1998; 46:489-97. View the summary.

Boger RH, Bode-Boger SM, Thiele W, etc. L-arginine restores the formation of vascular nitric oxide and can improve the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease. J Am Coll Cardiol 1998; 32: 1336-44. View the summary.

Bottari A, Belcaro G, Ledda A, etc. Lady Prelox can improve the sexual function of generally healthy women of childbearing age. Minerva Ginecol 2013; 65(4): 435-44. View the summary.

Brittenden J, Park KGM, Heys SD, etc. L-arginine stimulates the host defenses of breast cancer patients. Surgery 1994; 115: 205-12. View the summary.

Camarena Pulido EE, García Benavides L, Panduro Barón JG, etc. The efficacy of L-arginine in preventing preeclampsia in high-risk pregnancy: a double-blind, randomized, clinical trial. Hypertensive pregnancy. 2016;35(2):217-25. View the summary.

Ceremuzynski L, Chamiec T, Herbaczynska-Cedro K. The effect of oral L-arginine supplementation on exercise performance of patients with stable angina pectoris. Am J Cardiol 1997; 80: 331-3. View the summary.

Cesarone MR, Belcaro G, Scipione C, etc. Prevent vaginal dryness in perimenopausal women. Supplement Lady Prelox®. Minerva Ginecol. 2019;71(6):434-41. View the summary.

Chauhan A, More RS, Mullins PA, etc. L-arginine can reverse the endothelial dysfunction associated with aging in humans. J Am Coll Cardiol 1996; 28: 1796-804. View the summary.

Chen J, Gong X, Chen P, Luo K, Zhang X. The effects of L-arginine and sildenafil citrate on fetuses with intrauterine growth restriction: a meta-analysis. BMC is pregnant and childbirth. 2016; 16:225. View the summary.

Chen J, Wollman Y, Chernichovsky T, etc. The effect of oral high-dose nitric oxide donor L-arginine on men with organic erectile dysfunction: the results of a double-blind, randomized, placebo-controlled study. BJU Int 1999;83:269-73. View the summary.

Cheng JW, Balwin SN. L-arginine in the management of cardiovascular disease. Ann Pharmacother 2001;35:755-64. View the summary.

Chin-Dusting JP, Kaye DM, Lefkovits J, etc. The dietary supplement L-arginine cannot restore the endothelial function of the forearm resistance artery in patients with severe heart failure. J Am Coll Cardiol 1996; 27: 1207-13. View the summary.

Clark RH, Feleke G, Din M, etc. Nutritional treatment of acquired immunodeficiency virus-related weight loss using β-hydroxyβ-methylbutyric acid, glutamine, and arginine: a randomized, double-blind, placebo-controlled study. JPEN J Parenter Enteral Nutr 2000; 24:133-9. View the summary.

Clarkson P, Adams MR, Powe AJ, etc. Oral L-arginine can improve the endothelium-dependent expansion of young people with hypercholesterolemia. J Clin Invest 1996; 97: 1989-94. View the summary.

Creager MA, Gallagher SJ, Girard XJ, etc. L-arginine improves endothelium-dependent vasodilation in people with hypercholesterolemia. J Clin Invest 1992; 90: 1248-53. View the summary.

Daly JM, Lieberman MD, Goldfine J, etc. Enteral nutrition supplemented with arginine, RNA and omega-3 fatty acids in postoperative patients: immunology, metabolism, and clinical results. Surgery 1992; 112: 56-67. View the summary.

Daraei A, Ahmadizad S, Rahmani H, etc. L-arginine improves the endurance of overweight men with high-intensity intermittent exercise. Int J Sport Nutr Exerc Metab. 2020:1-9. View the summary.

de la Parra PR, González-Cruz MÁ, Ferreiro-Marin A, Casaubón-Garcín PR. Six cases of esophagitis induced by L-arginine are attached. Bol Med Hosp Infant Mex. 2020;77(1):38-41. View the summary.

de Luis DA, Izaola O, Cuellar L, etc. The effect of C-reactive protein and interleukin blood levels on postoperative arginine-enhanced enteral nutrition in patients with head and neck cancer. Eur J Clin Nutr 2003; 57:96-9. View the summary.

Debate IB, Booi DI, Wehrens KM, etc. Oral arginine supplementation and its effect on the donor site of skin grafts: a randomized clinical trial study. J burn nursing research. May to June 2009; 30(3): 417-26. View the summary.

Ehren I, Lundberg JO, Adolfsson J, Wiklund NP. The effect of L-arginine treatment on symptoms and bladder nitric oxide levels in patients with interstitial cystitis. Urology 1998; 52: 1026-9. View the summary.

El Taieb M, Hegazy E, Ibrahim A. Daily oral l-arginine plus tadalafil in diabetic patients with erectile dysfunction: a double-blind, randomized, controlled clinical trial. J sex medicine. 2019;16(9):1390-1397. View the summary.

El-Wakeel LM, Fouad FA, Saleem MD, Saber-Khalaf M. The efficacy and resistance of sildenafil/l-arginine combination compared with sildenafil alone in patients with organic erectile dysfunction​​ Susceptible. Andrology. 2020;8(1):143-147. View the summary.

Food and Drug Administration. Orphan designation and approval list. Orphan Product Development Office. Available at: www.fda.gov/orphan/designat/list.htm.

Feskens EJM, Oomen CM, Hogendoorn E, etc. Arginine intake and 25-year CHD mortality: a study in seven countries (letters). European Heart Journal 2001; 22: 611-2. View the summary.

Florence G, Coppola A, Izzo R, etc. The effect of oral administration of L-arginine on standard treatment for COVID-19 patients: a randomized, double-blind, placebo-controlled, parallel group trial. The results of the first interim analysis. Clinical Medicine 2021; 101125. View the summary.

Fontanive P, Saponati G, Iurato A, etc. The effect of L-arginine on the Minnesota Heart Failure Life Questionnaire Quality of Life scores in patients with chronic systolic heart failure. Med. Sci. Monit. 2009; 15: CR606-11. View the summary.

Fossell ET. The use of transdermal preparations of L-arginine to improve the temperature and flow of the feet of diabetic patients: a preliminary study. Diabetes Care 2004;27:284-5. View the summary.

Gallo L, Pecoraro S, Sarnacchiaro P, Silvani M, Antonini G. Daily treatment of erectile dysfunction with L-arginine 2,500 mg and tadalafil 5 mg combined and monotherapy: a prospective, randomized multicenter study. Sexual medicine. 2020:8(2):178-185. View the summary.

Grasemann H, Tullis E, Ratjen F. Randomized controlled trial of L-arginine inhalation in patients with cystic fibrosis. J cystic fiber. 2013;12(5):468-74. View the summary.

Hadi A, Arab A, Moradi S, Pantovic A, Clark CCT, Ghaedi E. The effect of L-arginine supplementation on blood lipids: a systematic review and meta-analysis of randomized controlled trials. Br J Nutr. 2019;122(9):1021-1032. View the summary.

Hafner P, Bonati U, Erne B, etc. Improving muscle function in Duchenne muscular dystrophy through L-arginine and metformin: an open-label, single-center, proof-of-concept study initiated by researchers. Public Science Library One. 2016;11(1):e0147634. View the summary.

Hambrecht R, Hilbrich L, Erbs S, etc. Correction of endothelial dysfunction in chronic heart failure: additional effects of exercise training and oral L-arginine supplements. J Am Coll Cardiol 2000; 35: 706-13. View the summary.

Hannemann J, Rendant-Gantzberg L, Zummack J, Hillig J, Eilermann I, Böger R. The single nucleotide polymorphisms in the arginase 1 and 2 genes differ from the circulating L-arginine concentrations in adults without supplementation and with L-arginine supplementation. J nutrition. 2020: nxaa325. View the summary.

East Y, Oshima T, Sasaki S, etc. Al. Angiotensin-converting enzyme inhibition, but not calcium antagonism, can improve the response of the renal vascular system to L-arginine in patients with essential hypertension. hypertension. July 1998; 32(1): 16-24. View the summary.

Houghton JL, Philbin EF, Strogatz DS, etc. The presence of African-American ethnicity predicts the improvement of coronary artery endothelial function after L-arginine supplementation. J Am Coll Cardiol 2002; 39: 1314-22. View the summary.

Hurt RT, Ebbert JO, Schroeder DR, etc. The use of L-arginine in the treatment of subjects with central obesity: a preliminary study. J diet supplement. March 2014; 11(1):40-52. View the summary.

Huynh NT, Tayek JA. Oral arginine can lower systemic blood pressure in patients with type 2 diabetes: its potential role in nitric oxide production. J Am Coll Nutr 2002;21:422-7.. View abstract.

Imai T, Matsuura K, Asada Y, etc. The preventive effect of HMB/Arg/Gln on radiation dermatitis in patients with concurrent radiotherapy and chemotherapy of head and neck cancer. Jpn J Clin Oncol 2014;44(5):422-7. View the summary.

Jude EB, Boulton AJ, Ferguson MW, Appleton I. The role of nitric oxide synthase isoforms and arginase in the pathogenesis of diabetic foot ulcers: the possible regulatory role of transforming growth factor 1. Diabetologia 1999; 42:748-57. View the summary.

Kanaya Y, Nakamura M, Kobayashi N, Hiramori K. The effect of L-arginine on lower limb vasodilator reserve and exercise capacity in patients with chronic heart failure. Heart 1999;81:512-7. View the summary.

Katz SD, Khan T, Zeballos GA, etc. The activity of the L-arginine-nitric oxide metabolic pathway is reduced in patients with congestive heart failure. Circulation 1999; 99: 2113-7. View the summary.

Kemen M, Senkal M, Homann HH, etc. Early postoperative enteral nutrition and arginine-omega-3 fatty acid and ribonucleic acid supplementation diet in cancer patients compared with placebo: an immunological evaluation of the impact. Crit Care Med 1995; 23: 652-9. View the summary.

Klotz T, Mathers MJ, Braun M, etc. The effectiveness of oral L-arginine in the first-line treatment of erectile dysfunction in a controlled crossover study. Urol Int 1999;63:220-3. View the summary.

Koçyigit Y, Yoca G, Karahan S, Ayhan Y, Yazici MK. L-arginine add-on treatment of schizophrenia: a randomized, double-blind, placebo-controlled, crossover study. The Turk Psikiyatri Derg. 2018;29(3):147-153. View the summary.

Koga Y, Povalko N, Inoue E, etc. L-arginine treatment of MELAS: 9-year, prospective, multi-center, clinical study. J nerve. 2018;265(12):2861-2874. View the summary.

Koting GE, Smith SD, Wheeler MA, etc. A randomized double-blind trial of oral L-arginine in the treatment of interstitial cystitis. J Urol 1999;161:558-65. View the summary.

Lerman A, Burnett JC Jr, Higano ST, etc. Long-term L-arginine can improve the coronary endothelial function of small blood vessels in humans. Circulation 1998; 97: 2123-8. View the summary.

Li J, Huang Z, Mei L, Li G, Li H. The anti-caries effect of arginine preparations in the body: a systematic review and meta-analysis. Caries research. 2015;49(6):606-17. View the summary.

Liao SY, Showalter MR, Linderholm AL, etc. L-arginine supplements for severe asthma. JCI insight. 2020; 5(13): e137777. View the summary.

Loscalzo J. Our knowledge and ignorance of L-arginine and NO. cycle. 2000 May 9; 101(18): 2126-9. View the summary.

Maxwell AJ, Zapien MP, Pearce GL, etc. A randomized trial of medical food for the dietary management of chronic and stable angina pectoris. J Am Coll Cardiol 2002; 39:37-45. View the summary.

McCaffrey MJ, Bose CL, Reiter PD, Stiles AD. The effect of L-arginine infusion on persistent pulmonary hypertension in newborns. Biol Neonatal 1995; 67: 240-3. View the summary.

Meirelles CM, Matsuura C. Acute supplementation of L-arginine neither affects strength performance nor nitric oxide production. J Sports Med Phys Fitness. March 2018; 58(3): 216-220. doi: 10.23736/S0022-4707.16.06680-9. View the summary.

Mercimek-Mahmutoglu S, Stöckler-Ipsiroglu S, Solomon GS. Creatine deficiency syndrome. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2014. View the summary.

Mitchell K, Lighter A, Armin H, etc. Arginine supplementation to prevent necrotizing enterocolitis in preterm infants: an updated systematic review. BMC Pediatrics September 10, 2014; 14:226. Review. View the summary.

Monti LD, Setola E, Lucotti PC, etc. The effect of long-term oral l-arginine supplementation on glucose metabolism: a randomized, double-blind, placebo-controlled trial. Diabetes obesity metabolism. October 2012; 14(10): 893-900. View the summary.

Morris CR, Kuypers FA, Lavrisha L, etc. A randomized, placebo-controlled trial of arginine therapy in children with sickle cell disease hospitalized for vascular occlusive pain. hematology. September 2013; 98(9): 1375-82. doi: 10.3324/haematol.2013.086637. View the summary.

Morris CR, Morris SM Jr, Hagar W, etc. Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease? Am J Respir Crit Care Med 2003;168:63-9. View the summary.

Mullen MJ, Wright D, Donald AE, etc. Atorvastatin but not L-arginine improves endothelial function in type I diabetes: a double-blind study. J Am Coll Cardiol 2000; 36: 410-6. View the summary.

Nazarian B, Fazeli Moghadam E, Asbaghi ​​O, etc. The effect of L-arginine supplementation on C-reactive protein and other inflammatory biomarkers: a systematic review and meta-analysis of randomized controlled trials. Supplement Ther Med. 2019;47:102226. View the summary.

Ohtsuka Y, Nakaya J. The effect of oral administration of L-arginine on Alzheimer's disease. Am J Med 2000; 108:439. View the summary.

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Oomen CM, van Erk MJ, Feskens E, etc. Arginine intake and the risk of death from coronary heart disease in elderly men. Arteriosclerosis Thrombosis Vascular Biology 2000; 20: 2134-9. View the summary.

Park KG. The immune and metabolic effects of L-arginine in human cancer. Proc Nutr Soc 1993;52:387-401. View the summary.

Parker JO, Parker JD, Caldwell RW, etc. The effect of L-arginine supplementation on the development of tolerance during continuous transdermal nitroglycerin treatment. J Am Coll Cardiol 2002; 39: 1199-203. View the summary.

Peters H, Noble NA. Dietary L-arginine in kidney disease. Smart Kidney 1996; 16: 567-75. View the summary.

Pichard C, Sudre P, Karsegard V, etc. A randomized, double-blind controlled study of 6-month oral nutritional supplementation of arginine and omega-3 fatty acids in HIV-infected patients. Swiss HIV Cohort Study. AIDS 1998; 12:53-63. View the summary.

Ralph AP, Waramori G, Pontoring GJ, etc. L-arginine and vitamin D adjuvant treatment of tuberculosis: a randomized, double-blind, placebo-controlled trial. Public Science Library One. August 14, 2013; 8(8): e70032. View the summary.

Principal TS, Bank AJ, Mullen KA, etc. A randomized, double-blind, placebo-controlled study of oral L-arginine supplementation in patients with heart failure. Circulation 1996; 93: 2135-41. View the summary.

Resnick DJ, Softness B, Murphy AR, etc. A case report of an allergic reaction to arginine. Ann Allergy Asthma Immunol 2002; 88: 67-8. View the summary.

Rezaei S, Gholamalizadeh M, Tabrizi R, Nowrouzi-Sohrabi P, Rastgoo S, Doaei S. The effect of L-arginine supplementation on maximal oxygen uptake: a systematic review and meta-analysis. Physiology Report 2021; 9(3): e14739. View the summary.

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Saffle JR, Wiebke G, Jennings K, etc. A randomized trial of immune-enhanced enteral nutrition in burn patients. J Trauma 1997; 42: 793-800, discussion 800-2. View the summary.

Sapienza MA, Kharitonov SA, Horvath I, etc. The effect of inhaled L-arginine on exhaled nitric oxide in normal and asthmatic subjects. Chest 1998; 53: 172-5. View the summary.

Schulman SP, Becker LC, Kass DA, etc. L-arginine treats acute myocardial infarction. A randomized clinical trial on the interaction of blood vessels and age in myocardial infarction (VINTAGE MI). Journal of the American Medical Association 2006;295:58-64. View the summary.

Senkal M, Kemen M, Homann HH, etc. Regulate the postoperative immune response of patients with upper gastrointestinal cancer through enteral nutrition and a diet rich in arginine, RNA and omega-3 fatty acids. Eur J Surg 1995;161:115-22. View the summary.

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Takano H, Lim HB, Miyabara Y, etc. Oral administration of L-arginine can enhance allergen-induced airway inflammation and interleukin-5 expression in mice. J Pharmacol Exp Ther 1998;286:767-71. View the summary.

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